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Cell Signaling Homework
Question
Cell Signaling Homework
Instructions
Answer the following questions based on the lecture videos and textbook reading.
- What is the difference between autocrine, paracrine, and endocrine? What is similar about all three of them?
- What is the difference between a secondary messenger and a phosphorylation cascade?
- What does crosstalk between signaling pathways mean?
- Predict what would happen if there was an insertion at the carboxy end of a GPCR – list the steps through the GPCR pathway you could go through before you ran into a problem.
- Predict what would happen if there was a mutation in a GPCR leading to loss of serine in the cytoplasmic domain of the GPCR – list the steps through the GPCR pathway you could go through before you ran into a problem.
- What are three possible options for re-setting cell surface GPCRs?
- How do cAMP and PKA lead to amplification of the signal transduction pathway?
This question is taken from Biol 303 – Intermediate Cell Biology » Fall 2021 » Homework