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Discussion Topic #1: Myasthenia Gravis
Discussion Topic #1: Myasthenia Gravis
In preparation for the essay section in exam 2, we will focus on the topic of neuromuscular disorders – specifically, Myasthenia Gravis. MG is discussed in Ch. 9 and is a great clinical case study to integrate your understanding of the nervous system and skeletal muscle.
Answer the following questions for this discussion board assignment:
- What is the problem for patients with MG?
- How does MG impact the normal mechanisms involved in the neuromuscular junction and, eventually, skeletal muscle contraction? **Discuss the the NORMAL mechanism at the NMJ for both neurotransmitter release at the presynaptic motor neuron AND the mechanism for skeletal muscle fiber contraction**
- Based on your understanding of the normal physiology mechanism of skeletal muscle contraction and the pathophysiology of MG, how do treatments using acetylcholinesterase inhibitors help MG patients?